Blz-945,Chemical. Cas: 953769-46-5, Each

Details:

Blz-945, adipogen life sciences. Chemical. Cas: 953769-46-5. Formula: c20h22n4o3s. Mw: 398.5. Blz945 is an orally active, potent and selective colony stimulating factor 1 receptor (csf-1r) inhibitor, which inhibits csf-1r activity with an ic(50) of 1nm and is more than 1000-fold selective against its closest receptor tyrosine kinase homologs c-kit and platelet-derived growth factor receptor beta (pdgfrbeta ) as well as more than 200 additional kinases, confirming the selectivity of the compound.