Concanamycin A (high purity),Chemical. CAS: 80890-47-7, Each

Details

Concanamycin A (high purity), AdipoGen Life Sciences. Chemical. CAS: 80890-47-7. Formula: C46H75NO14. MW: 866.1. Isolated from Streptomyces sp. Antibiotic. More potent and specific H -ATPase inhibitor than bafilomycin A1 (Prod. No. BVT-0252). Inhibits acidification of organelles such as lysosomes and the Golgi apparatus. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Blocks cell surface expression of viral glycoproteins without affecting their synthesis. Cytotoxic in a number of cell lines in a cell viability assay. Induces nitric oxide (NO) production.