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Cyclopamine,Chemical. CAS: 4449-51-8, Each

51.30

Details

Cyclopamine, AdipoGen Life Sciences. Chemical. CAS: 4449-51-8. Formula: C27H41NO2. MW: 411.6. Isolated from Veratrum californicum. Cell permeable steroidal alkaloid. Specific sonic hedgehog (Shh) signaling pathway inhibitor. Directly interacts/inhibits Smo (smoothened). Teratogenic and antitumor compound. Inhibits tumor cell growth and progression. Shows selective activity against Shh-dependent tumors. Blocks abnormal cell growth associated with oncogenic mutations of Ptch and Smo in fibroblasts. Arrests cell cycle at G0/G1. Apoptosis inducer.

Additional Information

SKU 1924583
UOM Each
UNSPSC 12161500
Manufacturer Part Number AGCN20028M001
CAS Number 4449-51-8
HS Code 2934999000
UN Number NULL
Proper Shipping Name CYCLOPAMINE
Molecular Formula C27H41NO2
Hazard Statement H341-H361
Precautionary Statements P201-P202-P280-P308+P313-P405-P501a
GHS GHS08
GHS (Pictogram)
Safety Statements 22-24/25
Hazard Code Xi