Jc-1 ,Chemical. Cas: 3520-43-2 And 47729-63-5, Each

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Jc-1 , adipogen life sciences. Chemical. Cas: 3520-43-2 and 47729-63-5. Formula: c25h27cl4in4. Mw: 652.2. The membrane-permeant dual-emission potential-sensitive jc-1 dye is widely used in apoptosis studies to monitor mitochondrial health by flow cytometry, fluorescence microscopy and in microplate-based fluorescent assays. Jc-1 dye can be used as an indicator of mitochondrial membrane potential in a variety of cell types, including myocytes and neurons, as well as in intact tissues and isolated mitochondria. Jc-1 accumulates in mitochondria, selectively generating an orange j-aggregate emission profile (590 nm) in healthy cells. After cell injury, as membrane potential decreases, jc-1 monomers are generated, resulting in a shift to green emission (529 nm).