Lactacystin, 133343-34-7, Mfcd01076525, 200 ug, Each

Details:

Lactacystin, adipogen life sciences. Chemical. Cas: 133343-34-7. Formula: c15h24n2o7s. Mw: 376.4. Isolated from streptomyces lactacystinnaeus strain om-6519. Induces neuritogenesis. Potent and selective irreversible proteasome inhibitor. Specifically inhibits 20s proteasome (mcp; multicatalytic complex). Blocks proteasome activity by targeting the catalytic beta-subunit. Apoptosis inducer. Anticancer compound. Upregulates hsp70 and hsp22. Induces differentiation and inhibits cell cycle progression in several tumor cell lines. Inhibits nf-kappab activation by inhibiting ikappab degradation. Cathepsin a inhibitor. Beta-secretase activity inhibitor. Anti-adipogenic. Autophagy inducer.