Necrostatin-1, 4311-88-0, Mfcd00056916, 5 mg, Each

Details:

Necrostatin-1, adipogen life sciences. Chemical. Cas: 4311-88-0. Formula: c13h13n3os. Mw: 259.3. Competitive indoleamine 2,3-dioxygenase (ido) inhibitor. Cell permeable, potent and selective necroptosis (a non-apoptotic form of programmed cell death) inhibitor. Showed neuroprotection in a murine model of ischemic brain injury in vivo. Selective and atp-competitive receptor-interacting protein kinase 1 (ripk1) inhibitor. Used in inflammatory and degenerative disease models to target ripk1. Suppresses autophagy and apoptosis in murine brain injury models. Cardioprotective and neuroprotective.