Orlistat,Chemical. Cas: 96829-58-2, Each

Details:

Orlistat, adipogen life sciences. Chemical. Cas: 96829-58-2. Formula: c29h53no5. Mw: 495.7. Synthetic. Originally isolated from streptomyces sp. Hypolipemic cell permeable and irreversible pancreatic, gastric and carboxylester lipase inhibitor. Anti-obesity and antihypercholesterolemic compound. Antitumor compound by inhibition of the thioesterase domain of fatty acid synthase (fasn). Anti-proliferative. Causes cell cycle arrest at g1 phase. Apoptosis inducer through caspase-3 activation. Sn-1-selective-diacylglycerol lipases alpha (daglalpha) inhibitor. Targets serine hydrolases in the nervous system, such as diacylglycerol lipase (dagl), which is responsible for the conversion of dag to 2-ag. Partially inhibits the hydrolysis of triglycerides and lowers the absorption of dietary fat, promoting weight loss. Promotes the sensitivity to trail in cancer cells by ros-mediated pathways.