PMA, Chemical. CAS: 16561-29-8;, Each
$ 62.10
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Details
PMA, AdipoGen Life Sciences. Chemical. CAS: 16561-29-8. Formula: C36H56O8. MW: 616.8. Semisynthetic. Most commonly-used phorbol ester. Binds to and activates protein kinase C (PKC) at nM concentrations. Induces cell growth arrest through a variety of pathways including the mitogen-activated protein kinases (MAPKs), p38 and c-Jun N-terminal kinase (JNK) pathways mediated by cyclin dependent kinase (CDK) inhibitors such as p21WAF1/CIP1, p27KIP1, p15 and p16. Potent mouse skin tumor promoter. Promoter of inducible NOS (iNOS; NOS II). Apoptosis inducer. Potential effective cancer therapeutic agent. Inhibitor of anti-lipolytic activity of insulin.
Additional Information
| SKU | 1924511 |
|---|---|
| UOM | Each |
| UNSPSC | 12161500 |
| Manufacturer Part Number | AGCN20010M001 |
| CAS Number | 16561-29-8 |
| HS Code | 2915390000 |
|---|---|
| UN Number | UN 2928 |
| Proper Shipping Name | PHORBOL 12-MYRISTATE 13-ACETATE |
| Packaging Group | PG II |
| Hazardous Class | 6.1 (a) |
| Label | .jpg) |
| Molecular Formula | C36H56O8 |
| EC Number | 605-413-5 |
| HIN | 66 |
| Hazard Statement | H300+H310+H330-H314-H317-H334-H351 |
| Precautionary Statements | P264-P280g-P302+P352a-P321-P332+P313-P362+P364 |
| Risk Statements | 38-36/37/38 |
| GHS | GHS05,GHS06,GHS08 |
| GHS (Pictogram) |    |
| Safety Statements | 36/37-26 |
| Hazard Code | Xi |
| Signal Word | Danger |
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