Radicicol,Chemical. Cas: 12772-57-5, Each

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Radicicol, adipogen life sciences. Chemical. Cas: 12772-57-5. Formula: c18h17clo6. Mw: 364.8. Isolated from gilmaniella sp. Antibiotic. Protein tyrosine kinase inhibitor. Has antifungal, antimalarial, antiangiogenic (in vivo), anti-inflammatory and antiviral activity. Cyclooxygenase-2 (cox-2) expression inhibitor without affecting cox-1 expression in lps-stimulated macrophages. Induces the differentiation of hl-60 cells into macrophages. Potent hsp90 inhibitor. Anticancer compound. In vivo rad/raf interaction inhibitor. Inhibitor of ap-1-, nf-kappab- and serum response factor (srf)-mediated transcription. Suppresses expression of inos (nos ii). Non-competitive inhibitor of atp citrate lyase. Dna topoisomerase vi and type ii dna topoisomerase inhibitor. Protects against lps/ifn-gamma-induced neuronal cell death. Apoptosis inducer.