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Sodium bicarbonate buffer system is important for several different cellular processes. It is one of the major buffering systems used to maintain the pH of mammalian blood and is also important in the acid-base homeostasis of living things, including humans. It tends to maintain a relatively constant plasma pH and counteract any force that would alter it. It is used to neutralize the pH of the chyme leaving the stomach and entering the small intestine. ApplicationsSodium bicarbonate buffer system is important for several different cellular processes. It is one of the major buffering systems used to maintain the pH of mammalian blood and is also important in the acid-base homeostasis of living things, including humans. It tends to maintain a relatively constant plasma pH and counteract any force that would alter it. It is used to neutralize the pH of the chyme leaving the stomach and entering the small intestine.SolubilityIt is soluble in water.NotesStore at 4°C in tightly closed container. Avoid inhalation. Wash thoroughly after handling. Avoid prolonged or repeated exposure.