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A soluble plasma glycoprotein, produced by the liver, that is converted by thrombin into fibrin during the blood coagulation process. Fibrinogen is a natural blood protein involved in the coagulation process. It is used instead of traditional sources of fibrinogen such as the blood products, fresh frozen plasma and cryoprecipitate. It helps in blood clot formation. General • Fibrinogen exists in blood as a dimer of three bonded, non-identical chains, FGA, FGG, and FGB• Fibrinogen is cleaved by thrombin to form fibrin, the most abundant component of blood clots Application • Fibrinogen can be used in a laboratory setting to form polymer hydrogels, particularly for use as a tissue scaffold• Fibrinogen may be useful in the research of neurodegeneration and brain injury; some evidence shows that it has a signaling role in neural progenitor cell
