Zeocin^t, 100 mg/ml in HEPES, sterile-filtered, Zeocin (phleomycin, CAS # 11031-11-1) is a broad-spectrum antibiotic that acts by intercalating DNA, Each

Details

Zeocin, a popular and effective antibiotic for the selection of vectors bearing the Sh ble gene in a variety of cells types (bacteria, eukaryotic microorganisms, plant and animal cells). Resistance to Zeocin is conferred by the Sh ble gene product, which inactivates Zeocin™ by binding to the antibiotic. Sh ble is a small gene, only 370bp in size, carried in a number of InvivoGen’s vectors. Zeocin is used as a selective agent in molecular genetics experiments. General Zeocin (phleomycin) is a glycopeptide from the bleomycin family of antibioticsZeocin intercalates DNA, producing double-stranded breaks and preventing cell divisionIt can chelate some active metals including cobalt, iron, and copperZeocin has antineoplastic and antifungal propertiesApplicationZeocin is useful for genetic selection experiment