CD29 Hamster anti-Mouse, Unlabeled, Clone: HM Tests1-1, BD, Hamster Monoclonal Antibody, Each

Details

The HM β;1-1 monoclonal antibody specifically binds to the 130-kDa integrin β;1 chain (CD29). CD29 is expressed on the cell surface as a heterodimer with one of the distinct integrin-α; chains. With α;1 through α;6 (CD49a through CD49f), it forms the VLA-1 through VLA-6 complexes, respectively, and with α;v (CD51), it forms α;vβ;1 integrin. It also associates with the integrin α;7 α;8, and α;9 chains in non-lymphoid tissues. As a result, CD29 has a broad tissue distribution, including lymphocytes, endothelia, smooth muscle, epithelia, and oocytes. This hamster mAb to a mouse leukocyte antigen has been observed to crossreact with similar populations of rat leukocytes. Source of the immunogen was purified mouse VLA-4 (α;4β;1, CD49d/CD29).