Benzo[A]Pyrene, 5 G, Un3077 9 / Pgiii, Each

Details:

Specifications synonym: 3,4-benzopyrene, 3,4-benzpyrene, benzo[def]chrysenecas number: 50-32-8empirical formula (hill notation): c20h12molecular weight: 252.31Beilstein registry number: 1911333ec number: 200-028-5mdl number: mfcd00003602pubchem substance id: 24891610application benzo[a]pyrene (pah), a polycyclic aromatic hydrocarbon pollutant, is used as a chemical carcinogen in experimental models of cancer. Carcinogenesis depends on it′s oxidation by cyp1a1 to benzo[a]pyrenediolepoxide, that forms depurinating adducts with dna that dissociate to form abasic lesions. Benzo[a]pyrene is a ligand for the arylhydrocarbon receptor (ahr), and some of its biological effects, including the induction of cyp1a1, appear to be mediated via activation of the ahr.Assay: ≥96% (hplc)bp: 495 °c(lit.)Mp: 177-180 °c(lit.)