CaM Kinase Kinase Mouse, Unlabeled, Clone: 6, BD, Mouse Monoclonal Antibody, Each

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Ca2 /Calmodulin (CaM)-dependent kinases are multifunctional kinases involved in a myriad of cellular functions such as neurotransmitter synthesis, long-term potentiation, and formation of spatial learning. A 68kDa CaM Kinase Kinase with homology to the Ca2 /CaM-dependent kinases, phosphorylates and activates Ca2 /CaM-dependent protein kinases I and IV, but not type II. This phosphorylation occurs on Ser/Thr residues and is Ca2 and CaM dependent. CaM Kinase Kinase is abundant in brain tissue, and is thought to be an upstream regulator in the Ca2 /CaM-dependent neural processes.Immunofluorescence, Immunohistochemistry, Immunoprecipitation, Western Blotting