CD184 Mouse anti-Human, APC, Clone: 12G5, BD, Mouse Monoclonal Antibody, Each

Details

Reacts with fusin (CXCR4), a seven-transmembrane domain, G-protein-linked glycoprotein. Fusin is expressed on a wide variety of CD4 and CD4- cells including those from spleen, brain and lung. It has been shown to function as a cofactor for infection with T-cell tropic strains of HIV-1 and also as a receptor for CD4-independent infection. 12G5 antibody has been reported to block CD4-independent infection by HIV-2 and CD4-dependent infection by some T-cell tropic isolates of HIV-1.Host Species: MouseClone: 12G5Isotype: IgG2a κSpecies Reactivity: HumanFlow Cytometry