CD25 Mouse anti-Human, Unlabeled, Clone: M-A251, BD, Mouse Monoclonal Antibody, Each

Details

Reacts with CD25, a 55kDa glycoprotein known as the low-affinity interleukin-2 receptor (IL-2R). CD25 is expressed on activated lymphocytes (T and B) and monocytes, and associates with the p75 high-affinity receptor chain to form the IL-2R complex. The CD25 molecule reveals three epitope regions: A, B, and C. M-A251 antibody recognizes epitope region B. CD25 expression on lymphocytes is upregulated by anti-CD3 or PHA stimulation. Soluble IL-2R is produced following inflammatory responses. This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.