CD27 Mouse anti-Human, APC, Clone: M-T271, BD, Mouse Monoclonal Antibody, Each

Details

The M-T271 monoclonal antibody specifically binds to the human form of CD27, a type I transmembrane, 110 kDa disulfide-linked homodimeric glycoprotein. The CD27 molecule is a lymphocyte-specific member of the TNFR/NGFR family. CD27 is expressed on a subset of human thymocytes and on the majority of mature T lymphocytes. This antibody also crossreacts with a major subset of peripheral blood lymphocytes and monocytes obtained from some non-human primates (NHP) including baboons as well as rhesus and cynomolgus macaques. CD27 expression is detected on the majority of CD3 lymphocytes and on a subset of CD20 cells derived from these NHP donors. The CD27 staining patterns on lymphocytes and monocytes from these NHP donors is similar to that observed with peripheral blood lymphocytes from normal human donors.