Cd34 Mouse Anti-Human, Pe, Clone: 563, Bd, Mouse Monoclonal Antibody, Each

Details:

The 563 monoclonal antibody specifically binds to cd34. Cd34 is a single-chain 105-120 kda heavily o-glycosylated transmembrane glycoprotein expressed on hematopoietic progenitor cells, vascular endothelium and some tissue fibroblasts. The intracellular chain of the cd34 antigen is a target for phosphorylation by activated protein kinase c suggesting that cd34 may play a role in signal transduction. Cd34 may play a role in adhesion of specific antigens to endothelium. Clone 563 belongs to the class iii epitope; it is resistant to neuraminidase, chymopapain and glycoprotease. This antibody is able to block the binding of other cd34 mabs like 581.