Calbiochem Amiloride, Hydrochloride, An inhibitor of angiogenesis, Each

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An inhibitor of angiogenesis. Inhibits capillary morphogenesis completely and reversibly at approximately 130μM. At low concentrations, acts as a potent and specific inhibitor of transmembrane Na entry and Na ,K -ATPase. Also acts as an inhibitor of urokinase-type plasminogen activator (uPA). Blocks smooth muscle responses to contractile stimuli and palytoxin-induced conductance in skeletal muscle. Reduces electrical potential across tubular epithelium. At higher concentrations, blocks the Na /H exchange pathway.