Calbiochem Cyclophilin A, Human, Recombinant, E. coli, Recombiant, human cyclophilin A expressed in E, Each

Details

Recombiant, human cyclophilin A expressed in E. coli . An ubiquitous enzyme that catalyzes the cis-trans- isomerization of X-Pro peptide bonds. Binds to proteins and acts as a chaperone in protein folding. Incorporates into HIV-1 virons and is believed to be essential for viral infectivity. Cyclophilin binds to the immunosuppressant Cyclosporin A (Cat. No. 239835). This complex then binds calcineurin (PP2B) and inhibits its phosphatase activity.