Calbiochem D609, Potassium Salt, Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (Ki = 5-10 μM), Each

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Selective inhibitor of phosphatidylcholine (PC)-specific phospholipase C (Ki = 5-10μM). Does not inhibit phosphatidylinositol-specific phospholipase C, phospholipase A, or phospholipase D. Also reported to inhibit LPS-stimulated ERK activation via its inhibitory effect on PLC. Inhibits angiogenesis by preventing the synthesis of basement membrane.