Calbiochem Gβγ Modulator II, Gallein, A cell-permeable xanthene compound that binds to Gβγ with high affinity (K, Each

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A cell-permeable xanthene compound that binds to Gβγ with high affinity (Kd ∽400nM derived from a surface plasma resonance binding study using Gβ1γ2) and blocks Gβγ-dependent cellular activities. Reported to exhibit in vivo prophylactic efficacy against carrageenan-induced neutrophil recruitment and tissue swelling in a murine paw edema model via either intraperitoneal or oral administration.