Calbiochem™ Hmtase Inhibitor Ii, Chaetocin, Each

Details:

A naturally occurring cell-permeable chaetomium fungal epi-dithio-diketopiperazine that potently inhibits the h3k9 histone methyltransferase activity of drosophila melanogaster su(var)3-9 and its human homologue suv39h1 (ic50 = 600 and 800 nm, respectively) in a sam-competitive manner, while exhibiting much reduced potency against murine g9a or neurospora crassa dim5 h3k9 hmt (ic