GANT61 >98% (HPLC), 25 mg, Each

Details

Specifications Synonym: 2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis[N,N-dimethyl-benzenamine, NSC 136476CAS Number: 500579-04-4Empirical Formula (Hill Notation): C27H35N5Molecular Weight: 429.60Biochem/physiol Actions: GANT61 blocks hedgehog pathway signaling by inhibiting the transcripional activity of Gli1 (IC50 = 5 µM). GANT 61 led to a regression of 22Rv1 human prostate tumor cell xenografts in nude mice.Assay: =98% (HPLC)Form: PowderColor: White to off-whiteSolubility: DMSO: >2 mg/mL