$ 369.91
Details
The novel core bead technology and multimodal, octylamine ligand give Capto Core 700 dual functionality, size exclusion, and binding chromatography in one chromatography medium (resin).For intermediate purification and polishing of viruses and other large biomolecules (Mr > 700 000) in flowthrough mode. Significantly improved productivity and higher flow rates compared with gel filtration methods.Straightforward optimization due to flowthrough chromatography and robust performance. Convenient small-scale purification, process development, and scale-up using prepacked HiTrap and HiScreen columns. Capto Core 700 is composed of a ligand-activated core and inactive shell. The inactive shell excludes large molecules (cut off ∼ Mr 700 000 [700 kDa]) from entering the core through the pores of the shell.The core of each bead is functionalized with ligands that are both hydrophobic and positively charged, resulting in a highly efficient multimodal binding of various contaminants small enough to enter the core.The multimodal ligands ensure strong binding with most impurities over a wide range of pH and salt concentrations. Bound impurities are removed from the beads by cleaning-in-place (CIP) procedures using NaOH and in most cases, a solvent.This product(s) resides on a Fisher Scientific GSA or VA contract. If you are viewing this page as a nonregistered user, the price(s) displayed is List Price. To view your GSA or VA contract pricing, log in using your account number, or become a registered user by contacting one of our Customer Service teams. You can also view your contract price by searching for this item(s) on GSA Advantage. To place an order, contact Fisher Scientific Customer Service.