HSD11B1 Goat anti-Human, Polyclonal Antibody, Abnova, Goat polyclonal antibody raised against synthetic peptide of HSD11B1, Each

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The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeqSequence: CTSYNMDRFINK