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Specifications Synonym: Hyaluronate 4-glycanohydrolase, HyaluronoglucosaminidaseCAS Number: 37326-33-3EC Number: 253-464-3Enzyme Commission (EC) Number: 3.2.1.35MDL Number: MFCD00131351Biochem/physiol Actions Hyaluronidase degrades hyaluronan and has been found to be inappropriately regulated during cancer progression.1,2These enzymes randomly cleave ß-N-acetylhexosamine-[1?4] glycosidic bonds in hyaluronic acid, chondroitin, and chondroitin sulfates.Unit Definition One unit will cause a change in A600 of 0.330 per minute at pH 5.7 at 37 °C in a 2.0 ml reaction mixture (45 minute assay).Type: Type IV-SForm: lyophilized powder (essentially salt-free)Mol. Wt.: mol wt ~55 kDa (four subunits of 14 kDa each)Storage Temp.: -20°CGene Information: Cow ... HYAL1(515397), HYAL2(281838)
