Mac-3 Rat Anti-Mouse, Unlabeled, Clone: M3/84, Bd, Rat Monoclonal Antibody, Each

Details:

The m3/84 antibody reacts with the 110kda mac-3 antigen expressed on mouse mononuclear phagocytes. Surface expression of the 92 to 110kda glycoprotein antigen increases during differentiation of monocytes to activated peritoneal macrophages. The m3/84 mab can detect cd107b antigen on tissue macrophages, thioglycollate-elicited peritoneal macrophages, and some myeloid cell lines, but not on lymphocytes or monocytes. In the bone marrow, very few cells display cd107b antigen on the surface, but a large proportion express cytoplasmic cd107b. The m3/84 antibody has also been reported to stain dendritic cells and endothelium in sections of thymus (both medulla and cortex), lymph nodes, spleen (white pulp), and gut-associated lymphoid tissue.