$ 540.00
Details
NMDA Receptor 1 (N-methyl-D-aspartate receptor 1) which belongs to the glutamate receptor channel superfamily, in humans is encoded by gene GRIN1 (Glutamate [NMDA] receptor subunit zeta-1) located on chromosome 9q34.3. Different NRI subunits are expressed by splicing of the GRINI gene sequence. Glutamate receptors are highly permeable to Ca , important for controlling plasticity, memory and learning. NMDA receptors are important for the functioning of the nervous system.This antibody is predicted to react with mouse based on sequence homology.ABfinity™ recombinant antibodies are rabbit monoclonal antibodies, unmatched for producing superior results. ABfinity™ antibodies are developed by immunizing animals, screening for functionality, cloning the immunogen-specific antibody genes into high-level mammalian expression vectors, produced on a large scale and purified with Protein A. ABfinity™ oligoclonal antibodies comprise a selection of multiple different recombinant monoclonal antibodies, providing the best of both worlds—the sensitivity of a polyclonal antibody with the specificity of a monoclonal, all delivered with the consistency only found in a recombinant antibody. While functionally the same as a polyclonal antibody—recognizing multiple epitope sites on the target and producing higher detection sensitivity for low abundance targets when compared with monoclonal antibodies—an oligoclonal antibody has a known mixture of light and heavy chains. This exact population can be produced in every lot, circumventing the biological variability typically associated with polyclonal antibody production.Intact IgG appears on a non-reducing gel as ∽150kDa band and upon reduction generating a ∽25kDa light chain band and a ∽50kDa heavy chain.
