Prodrug of 5-FU and inhibitor of thymidylate synthase that is used to treat various cancers. It inhibits DNA synthesis, Each

Details:

Capecitabine is an antifolate anticancer chemotherapeutic that acts as a prodrug of 5-fluorouracil (5-FU), a fluoropyrimidine carbamate that inhibits thymidylate synthase. Capecitabine is converted to 5-FU by thymidine phosphorylase in vivo. Capecitabine displays varying efficacy in the treatment of colorectal, metastatic breast, prostate, ovarian, and pancreatic cancers.