DNA-PKcs Ab-1 Monoclonal Antibody, Inhibit DNA-dependent phosphorylation and perform other studies with DNA-PKcs Ab-1, Mouse Monoclonal Antibody, Each

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DNA-dependent Protein Kinase (DNA-PKcs) phosphorylates transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. In vivo, it is involved in repairing double strand DNA breaks. Host Species: MouseClone: 18-2Isotype: IgG1Species Reactivity: Human and Rat. Others not known.Epitope: aa 1-2713Immunogen: Human DNA-dependent Protein Kinase purified from HeLa cellsMolecular Weight: 460 kDaPositive Control: LS174T cells, TonsilCellular Localization: Nuclear Recommended for:Immunohistochemistry (Formalin/paraffin)Western BlottingImmunofluorescenceImmunoprecipitation (Native and denatured)Inhibits (50%) DNA-dependent Phosphorylation Note:USA: RUO; Int'l: RUO