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Thrombospondin is a protein from platelet a-granules. It is secreted at sites of platelet activation and aggregation and is involved in the processes of chemotaxis, adhesion, proliferation and differentiation of leukocytes, fibroblasts, smooth muscle and endothelial cells. Host Species: MouseClone: A6.1Isotype: IgG1Species Reactivity: Human, Cow, Pig, Horse, Dog, Sheep, Mouse and Rat. Others not known.Epitope: Collagen Type V-binding domain of TSPImmunogen: Reduced and alkylated purified human TSP (fully denatured) from the supernatant of thrombin-activated plateletsMolecular Weight: ∽450kDa (nonreduced), 170 to 180kDa (reduced)Positive Control: Tonsil or PlacentaCellular Localization: Secretory granules, Golgi complex, endoplasmic reticulum, extracellular matrix Recommended for:Immunohistochemistry (Formalin/paraffin)Western BlottingImmunofluorescenceImmunoprecipitation (Native verified)Electron MicroscopyFlow Cytometry Note:USA: RUO; Int'l: RUO
