Tip-39 1mg, Each

Details:

Tip-39^ 1mg tuberoinfundibular peptide, tip-39, originally isolated from bovine hypothalamus was found to be a potent and selective agonist of the pth2 receptor which regulates pituitary hormone secretion and spinal cord regions involved in pain perception. Synthetic tip-39 activated the human and rat pth2 receptors with ec50 of 0.5 ª 0.12 Nm and 0.8 ª 0.3 Nm, respectively. Tip-39 was much more potent than pth (ec50 = 49 ª 23 nm) at the rat pth2 receptor. The discovery of tip-39 provides an important tool for the investigation of the pth2 receptor functions inside and outside the nervous system. Cas: 277302-47-3 c202h325n61o54s fw: 4504.25 . Ti