TNF Mouse anti-Human, APC, Clone: MAB11, BD, Mouse Monoclonal Antibody, Each

Details

The MAb11 antibody reacts with human tumor necrosis factor (TNF, formerly known as TNF-α) protein. TNF is an efficient paracrine and endocrine mediator of inflammatory and immune functions. It regulates the growth and differentiation of a variety of cell types. TNF is cytotoxic for transformed cells when in conjunction with IFN-γ. It is secreted by activated monocytes/macrophages and other cells such as B cells, T cells and fibroblasts. The immunogen used to generate the MAb11 hybridoma was recombinant human TNF. The use of the MAb11 antibody has been reported to cross-react with TNF of rhesus monkey.Host Species: MouseClone: MAb11Isotype: IgG1 κSpecies Reactivity: Non-human primateImmunogen: Recombinant Human TNFIntracellular Staining