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A01, High affinity Smurf1 inhibitor; enhances BMP signaling, Each

363.66

Details

A01 is a high affinity Smurf1 E3 ubiquitin ligase inhibitor (Kd = 3.7 nM). Attenuates Smurf1-mediated Smad 1/5 degradation and enhances BMP signaling. Potentiates BMP-2-induced osteoblastic activity in C2C12 myoblasts and MC3T3-E1 osteoblast precursor cells.

Additional Information

SKU 10526662
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5397/10