Bms 195614, Selective Rarα Antagonist, Each

Details:

Bms 195614 is a neutral retinoic acid receptor (rar) α-selective antagonist (ki = 2.5 Nm). Displays no significant effect on nuclear receptor corepressor (ncor) binding; moderately decreases smrt binding to rar. Antagonizes agonist-induced coactivator (coa) recruitment.