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JJKK 048, Potent and selective MAGL inhibitor, Each

473.28

Details

JJKK 048 is a potent and selective monoacylglycerol lipase (MAGL) inhibitor (IC50 = 0.4 nM). Exhibits >13,000 and ∽630-fold selectivity for MAGL over FAAH and ABHD6, respectively. Increases brain levels of 2-arachidonoylglycerol (2-AG) levels in mice in vivo. Promotes analgesia in pain models.

Additional Information

SKU 10514402
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5206/10