ml 365, Potent And Selective K2p3.1 (Task-1) Channel Blocker, Each

Details:

Ml 365 is a potent and selective task-1 (k2p3.1/Kcnk3) channel blocker (ic50 values are 4 and 390 nm at task-1 and task-3, respectively). Displays little or no inhibition at kir2.1, Voltage-gated potassium channels, kcnq2 and kv11.1 (Herg).