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MM 102, WDR5/MLL interaction inhibitor, Each

600.30

Details

MM 102 is a potent WDR5/MLL interaction inhibitor (IC50 = 2.4 nM). Inhibits MLL1 methyltransferase activity and MLL-1-induced HoxA9 and Meis-1 gene expression in leukemia cells expressing the MLL1-AF9 fusion gene. Also inhibits cell growth and induces apoptosis in leukemia cells harbouring MLL1 fusion proteins.

Additional Information

SKU 10496820
UOM Each
UNSPSC 12161500
Manufacturer Part Number 5307/10
CAS Number 1883545-52-5