Sb 224289 Hydrochloride, Selective 5-Ht1b Antagonist, Each

Details:

Sb 224289 hydrochloride is a selective 5-ht1b receptor antagonist (pki = 8.2). Displays > 60-fold selectivity over 5-ht1d, 5-ht1a, 5-ht1e, 5-ht1f, 5-ht2a and 5-ht2c receptors in radioligand binding and functional assays. Centrally active following oral administration in vivo.