Tcb-2, High Affinity And Potent 5-Ht2a Agonist, Each

Details:

Tcb-2 is a high affinity 5-ht2a receptor agonist (ki values are 0.73 And 0.75 Nm for rat and human receptors respectively). Potently stimulates ip3 accumulation in nih3t3 cells stably expressing rat 5-ht2a receptors (ec50 = 36 nm). Induces head twitches and hypothermia in mice following i.P. Administration.