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UC 112, IAP and XIAP inhibitor; antitumor, Each

443.70

Details

UC 112 is an iAP inhibitor (IC50 values from 0.7 - 3.4 μM); inhibits cell growth in multiple cancer cell lines and in a melanoma xenograft model in vivo. Also suppresses X-linked inhibitor of apoptosis protein (XIAP) and survivin levels. Inhibits the growth of P-glycoproteins and activates caspase-3/7 and caspase-9.

Additional Information

SKU 10178823
UOM Each
UNSPSC 41116105
Manufacturer Part Number 5251/10